Recombinant Estrogen Receptor alpha Monoclonal Antibody

• Background:

  This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters.

• Description:

  This is a Recombinant Estrogen Receptor alpha Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  DKFZp686N23123, ER alpha, ER, ER-alpha, Era, ESR, ESR1, ESR1, ESRA, Estradiol receptor, Estrogen nuclear receptor alpha, Estrogen receptor 1, Estrogen receptor alpha 3*,4,5,6,7*/822 isoform, Estrogen receptor alpha, Estrogen receptor alpha delta 3*,4,5,6,7*,8*/941 isof

• Gene ID:

  2099

• Swiss Prot:

  P03372

• Reactivity:

  Human

• Immunogen:

  A synthetic peptide of human Estrogen Receptor alpha

• Clonality:

  Monoclonal

• Conjugation:

  Unconjugated

• Type:

  Recombinant Antibody

• Applications:

  WB, IHC-P, IF

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  300 μg/mL

• Dilution:

  WB 1:500-1:1000, IHC 1:50-1:100, IF 1:20-1:100

• Buffer:

  50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  119kDa

• Observed Molecular Weight:

  125kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG