Estrogen Receptor alpha Polyclonal Antibody

• Background:

  This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined.

• Description:

  This is a Estrogen Receptor alpha Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1, ER alpha

• Gene ID:

  2099

• Swiss Prot:

  P03372

• Reactivity:

  Human, Mouse

• Immunogen:

  Recombinant fusion protein of human Estrogen Receptor alpha (NP_000116.2) .

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:1000-1:4000

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  35 kDa/47 kDa/53 kDa/66 kDa

• Observed Molecular Weight:

  75 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG