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NR3C2 Polyclonal Antibody

CAT: 0866-RD90384A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD90384A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting. Defects in this gene are also associated with early onset hypertension with severe exacerbation in pregnancy. Alternative splicing results in multiple transcript variants.
Description
This is a NR3C2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
NR3C2, MCR, MLR, MR, NR3C2VIT
Gene ID
4306
Swiss Prot
P08235
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human Mineralocorticoid receptor
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC, IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000, IHC 1:50-1:200, IF 1:50-1:200
Buffer
PBS with 0.01% thiomersal,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
13kDa/15kDa
Observed Molecular Weight
14KDa
Host or Source
Rabbit
Isotype
IgG

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