NR3C1 Polyclonal Antibody

CAT: 0866-RD81555A-01Size: 60 μLDry Ice: NoHazardous: No
CAT#:0866-RD81555A-01Size:60 μL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription, and as a regulator of other transcription factors. This receptor is typically found in the cytoplasm, but upon ligand binding, is transported into the nucleus. It is involved in inflammatory responses, cellular proliferation, and differentiation in target tissues. Mutations in this gene are associated with generalized glucocorticoid resistance. Alternative splicing of this gene results in transcript variants encoding either the same or different isoforms. Additional isoforms resulting from the use of alternate in-frame translation initiation sites have also been described, and shown to be functional, displaying diverse cytoplasm-to-nucleus trafficking patterns and distinct transcriptional activities (PMID:15866175) .
Description
This is a NR3C1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
GCCR, GCR, GCRST, GR, GRL, NR3C1
Gene ID
2908
Swiss Prot
P04150
Reactivity
Human
Immunogen
Recombinant fusion protein of human NR3C1 (NP_001191194.1) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000 IF 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
49-85 kDa
Observed Molecular Weight
105 kDa
Host or Source
Rabbit
Isotype
IgG

Related Products

CatalogName
RD90384A-01NR3C2 Polyclonal Antibody
RD-NR3C1-Mu-01Mouse Nuclear Receptor Subfamily 3, Group C, Member 1 (NR3C1) ELISA Kit
RD-NR3C1-Hu-96TestsHuman Nuclear Receptor Subfamily 3, Group C, Member 1 (NR3C1) ELISA Kit
RDR-NR3C1-Ra-48TestsRat Nuclear Receptor Subfamily 3, Group C, Member 1 (NR3C1) ELISA Kit
RDR-NR3C1-Hu-48TestsHuman Nuclear Receptor Subfamily 3, Group C, Member 1 (NR3C1) ELISA Kit
RD-NR3C1-Ra-01Rat Nuclear Receptor Subfamily 3, Group C, Member 1 (NR3C1) ELISA Kit
RDR-NR3C1-Hu-01Human Nuclear Receptor Subfamily 3, Group C, Member 1 (NR3C1) ELISA Kit
RD-NR3C1-Hu-01Human Nuclear Receptor Subfamily 3, Group C, Member 1 (NR3C1) ELISA Kit
RD-NR3C1-Ra-48TestsRat Nuclear Receptor Subfamily 3, Group C, Member 1 (NR3C1) ELISA Kit
RD-NR3C1-Ra-96TestsRat Nuclear Receptor Subfamily 3, Group C, Member 1 (NR3C1) ELISA Kit

Alternative Products

CatalogName
MBS2530268-01NR3C1 Polyclonal Antibody
MF-0081654-01Anti-NR3C1 Polyclonal Antibody
E10G08372NR3C1 Rabbit Polyclonal Antibody
MBS8125277-01Anti-NR3C1 Antibody, Rabbit Polyclonal
MF-0081655-01Anti-NR3C1 Polyclonal Antibody 2
NB120-3579Rabbit Polyclonal GR/NR3C1 Antibody
HY450014-01Anti-Human NR3C1 Polyclonal Antibody
MBS7119518-01NR3C1 Antibody

Popular Products