CNOT7 Polyclonal Antibody

• Background:

  The protein encoded by this gene binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The encoded protein downregulates the innate immune response and therefore provides a therapeutic target for enhancing its antimicrobial activity against foreign agents. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and X.

• Description:

  This is a CNOT7 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  CNOT7, CAF-1, CAF1, Caf1a, hCAF-1

• Gene ID:

  29883

• Swiss Prot:

  Q9UIV1

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein of human CNOT7

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB, IHC

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1mg/mL

• Dilution:

  WB 1:200-1:2000, IHC 1:50-1:200

• Buffer:

  PBS with 0.01% thiomersal,50% glycerol, pH7.3.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  47kDa/55kDa/61kDa

• Observed Molecular Weight:

  61kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG