F11R Polyclonal Antibody

• Background:

  Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established.

• Description:

  This is a F11R Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  F11R, CD321, JAM, JAM1, JAMA, JCAM, KAT, PAM-1

• Gene ID:

  50848

• Swiss Prot:

  Q9Y624

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein of human F11R

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB, IHC

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:2000, IHC 1:50-1:200

• Buffer:

  PBS with 0.01% thiomersal,50% glycerol, pH7.3.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  68kDa

• Observed Molecular Weight:

  69KDa

• Host or Source:

  Rabbit

• Isotype:

  IgG