PTPN2 Polyclonal Antibody

• Background :

  The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of this PTP, which suggested the roles in growth factor mediated cell signaling. Multiple alternatively spliced transcript variants encoding different isoforms have been found. Two highly related but distinctly processed pseudogenes that localize to chromosomes 1 and 13, respectively, have been reported.

• Description :

  This is a PTPN2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  PTPN2, PTN2, PTPT, TC-PTP, TCELLPTP, TCPTP, tyrosine-protein phosphatase non-receptor type 2

• Gene ID :

  5771

• Swiss Prot :

  P17706

• Reactivity :

  Human

• Immunogen :

  Recombinant fusion protein of human PTPN2

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  WB, IF

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Concentration :

  1mg/mL

• Dilution :

  WB 1:500-1:2000, IF 1:50-1:200

• Buffer :

  PBS with 0.05% proclin300,50% glycerol, pH7.3.

• Storage Conditions :

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  250kDa

• Observed Molecular Weight :

  Refer to figures

• Host or Source :

  Rabbit

• Isotype :

  IgG