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CHEK1 Polyclonal Antibody

CAT: 0866-RD84616A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD84616A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcript variants have been found for this gene.
Description
This is a CHEK1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
CHEK1, CHK1
Gene ID
1111
Swiss Prot
O14757
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide of human CHEK1
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC, IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
43 kDa/50 kDa/54 kDa
Observed Molecular Weight
54 kDa
Host or Source
Rabbit
Isotype
IgG

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