Products for Research Use Only

MDH1 Polyclonal Antibody

CAT: 0866-RD84571A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD84571A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes an enzyme that catalyzes the NAD/NADH-dependent, reversible oxidation of malate to oxaloacetate in many metabolic pathways, including the citric acid cycle. Two main isozymes are known to exist in eukaryotic cells: one is found in the mitochondrial matrix and the other in the cytoplasm. This gene encodes the cytosolic isozyme, which plays a key role in the malate-aspartate shuttle that allows malate to pass through the mitochondrial membrane to be transformed into oxaloacetate for further cellular processes. Alternatively spliced transcript variants have been found for this gene. A recent study showed that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Pseudogenes have been identified on chromosomes X and 6.
Description
This is a MDH1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
MDH1, HEL-S-32, MDH-s, MDHA, MGC:1375, MOR2
Gene ID
4190
Swiss Prot
P40925
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human MDH1 (NP_005908.1) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
27 kDa/36 kDa/38 kDa
Observed Molecular Weight
36 kDa
Host or Source
Rabbit
Isotype
IgG