STAT2 Polyclonal Antibody

CAT: 0866-RD78902A-01Size: 20 µLDry Ice: NoHazardous: No
CAT#:0866-RD78902A-01Size:20 µL
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus.
Description
This is a STAT2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
Homo sapiens interferon alpha induced transcriptional activator, interferon alpha induced transcriptional activator, ISGF 3, ISGF3, MGC59816, P113, signal transducer and activator of transcription 2 113kD, Signal transducer and activator of transcription 2, STAT1
Swiss Prot
P52630
Accession Number
NP_005410
Reactivity
Human
Immunogen
Synthetic peptide of human STAT2
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
0.5 mg/mL
Dilution
WB 1:500-1:2000, IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
98 kDa
Host or Source
Rabbit
Isotype
IgG

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