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ATP2B2 Polyclonal Antibody

CAT: 0866-RD84120A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD84120A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 2. Alternatively spliced transcript variants encoding different isoforms have been identified.
Description
This is a ATP2B2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
ATP2B2, PMCA2, PMCA2a, PMCA2i
Gene ID
491
Swiss Prot
Q01814
Reactivity
Mouse, Rat
Immunogen
Recombinant fusion protein of human ATP2B2 (NP_001674.2) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
127-136 kDa
Observed Molecular Weight
137 kDa
Host or Source
Rabbit
Isotype
IgG

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