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NPHP1 Polyclonal Antibody

CAT: 0866-RD83992A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD83992A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a protein with src homology domain 3 (SH3) patterns. This protein interacts with Crk-associated substrate, and it appears to function in the control of cell division, as well as in cell-cell and cell-matrix adhesion signaling, likely as part of a multifunctional complex localized in actin- and microtubule-based structures. Mutations in this gene cause familial juvenile nephronophthisis type 1, a kidney disorder involving both tubules and glomeruli. Defects in this gene are also associated with Senior-Loken syndrome type 1, also referred to as juvenile nephronophthisis with Leber amaurosis, which is characterized by kidney and eye disease, and with Joubert syndrome type 4, which is characterized by cerebellar ataxia, oculomotor apraxia, psychomotor delay and neonatal breathing abnormalities, sometimes including retinal dystrophy and renal disease. Multiple transcript variants encoding different isoforms have been found for this gene.
Description
This is a NPHP1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
NPHP1, JBTS4, NPH1, SLSN1
Gene ID
4867
Swiss Prot
O15259
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human NPHP1 (NP_001121651.1) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000 IF 1:50-1:100
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
69 kDa/77 kDa/83 kDa
Observed Molecular Weight
83 kDa
Host or Source
Rabbit
Isotype
IgG

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