PTPRN Polyclonal Antibody

• Background:

  The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus. Alternate splicing results in multiple transcript variants.

• Description:

  This is a PTPRN Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  PTPRN, IA-2, IA-2/PTP, IA2, ICA512, R-PTP-N

• Gene ID:

  5798

• Swiss Prot:

  Q16849

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein of human PTPRN (NP_001186693.1) .

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:2000

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  96 kDa/102 kDa/105 kDa

• Observed Molecular Weight:

  66 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG