Products for Research Use Only

TNFSF12 Polyclonal Antibody

CAT: 0866-RD83413A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD83413A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue distribution. This cytokine, which exists in both membrane-bound and secreted forms, can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. Alternative splicing results in multiple transcript variants. Some transcripts skip the last exon of this gene and continue into the second exon of the neighboring TNFSF13 gene; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13.
Description
This is a TNFSF12 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
TNFSF12, APO3L, DR3LG, TNLG4A, TWEAK
Gene ID
8742
Swiss Prot
O43508
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human TNFSF12 (NP_003800.1) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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