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DDX3X Polyclonal Antibody

CAT: 0866-RD83399A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD83399A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a member of the large DEAD-box protein family, that is defined by the presence of the conserved Asp-Glu-Ala-Asp (DEAD) motif, and has ATP-dependent RNA helicase activity. This protein has been reported to display a high level of RNA-independent ATPase activity, and unlike most DEAD-box helicases, the ATPase activity is thought to be stimulated by both RNA and DNA. This protein has multiple conserved domains and is thought to play roles in both the nucleus and cytoplasm. Nuclear roles include transcriptional regulation, mRNP assembly, pre-mRNA splicing, and mRNA export. In the cytoplasm, this protein is thought to be involved in translation, cellular signaling, and viral replication. Misregulation of this gene has been implicated in tumorigenesis. This gene has a paralog located in the nonrecombining region of the Y chromosome. Pseudogenes sharing similarity to both this gene and the DDX3Y paralog are found on chromosome 4 and the X chromosome. Alternative splicing results in multiple transcript variants.
Description
This is a DDX3X Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
DDX3X, CAP-Rf, DBX, DDX14, DDX3, HLP2, MRX102
Gene ID
1654
Swiss Prot
O00571
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human DDX3X (NP_001347.3) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC, IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
71 kDa/73 kDa
Observed Molecular Weight
80 kDa
Host or Source
Rabbit
Isotype
IgG

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