PIDD Polyclonal Antibody

CAT: 0866-RD83149A-01Size: 60 μLDry Ice: NoHazardous: No
CAT#:0866-RD83149A-01Size:60 μL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene contains a leucine-rich repeat and a death domain. This protein has been shown to interact with other death domain proteins, such as Fas (TNFRSF6) -associated via death domain (FADD) and MAP-kinase activating death domain-containing protein (MADD), and thus may function as an adaptor protein in cell death-related signaling processes. The expression of the mouse counterpart of this gene has been found to be positively regulated by the tumor suppressor p53 and to induce cell apoptosis in response to DNA damage, which suggests a role for this gene as an effector of p53-dependent apoptosis. Alternative splicing results in multiple transcript variants.
Description
This is a PIDD Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
PIDD1, LRDD, PIDD
Gene ID
55367
Swiss Prot
Q9HB75
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human PIDD (NP_665893.2) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC, IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:1000 IHC 1:50-1:200 IF 1:50-1:100
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
33 kDa/37 kDa/58 kDa/66 kDa/82 kDa/97 kDa/99 kDa
Observed Molecular Weight
100-110 kDa
Host or Source
Rabbit
Isotype
IgG

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