PIDD Polyclonal Antibody

• Background:

  The protein encoded by this gene contains a leucine-rich repeat and a death domain. This protein has been shown to interact with other death domain proteins, such as Fas (TNFRSF6) -associated via death domain (FADD) and MAP-kinase activating death domain-containing protein (MADD), and thus may function as an adaptor protein in cell death-related signaling processes. The expression of the mouse counterpart of this gene has been found to be positively regulated by the tumor suppressor p53 and to induce cell apoptosis in response to DNA damage, which suggests a role for this gene as an effector of p53-dependent apoptosis. Alternative splicing results in multiple transcript variants.

• Description:

  This is a PIDD Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  PIDD1, LRDD, PIDD

• Gene ID:

  55367

• Swiss Prot:

  Q9HB75

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein of human PIDD (NP_665893.2) .

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB, IHC, IF

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:1000 IHC 1:50-1:200 IF 1:50-1:100

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  33 kDa/37 kDa/58 kDa/66 kDa/82 kDa/97 kDa/99 kDa

• Observed Molecular Weight:

  100-110 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG