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PIDD (C) Antibody, Rabbit Polyclonal

CAT: 0013-GTR18212084Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18212084Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Rabbit polyclonal to PIDD. P53-induced protein with a death domain (PIDD) promotes apoptosis downstream of the tumor suppressor as component of the DNA damage/stress response pathway that connects p53/TP53 to apoptosis. PIDD associates with NEMO/IKBKG and RIP1 and enhances sumoylation and ubiquitination of NEMO/IKBKG which is important for activation of the transcription factor NF-kappa-B. PIDD also associates with CASP2/caspase-2 and CRADD/RAIDD, and induces activation of CASP2 which is an important regulator in apoptotic pathway.
UniProt
Q9HB75
Reactivity
Human, Mouse
Immunogen
C-terminal region of human PIDD
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Cell Biology
Concentration
100 μg/ml BSA
Dilution
WB:1:1000-1:3000
Purity
Affinity purification
Molecular Weight
100
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
WB: The apparent protein size on WB may be different from the calculated M.W. due to modifications.Experiment Notes: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the C-terminal region of human PIDD.
Tested Applications
WB
Host or Source
Rabbit
Preservative
0.01% NaN3

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