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GTPBP4 Polyclonal Antibody

CAT: 0866-RD83109A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD83109A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
GTP-binding proteins are GTPases and function as molecular switches that can flip between two states: active, when GTP is bound, and inactive, when GDP is bound. 'Active' in this context usually means that the molecule acts as a signal to trigger other events in the cell. When an extracellular ligand binds to a G-protein-linked receptor, the receptor changes its conformation and switches on the trimeric G proteins that associate with it by causing them to eject their GDP and replace it with GTP. The switch is turned off when the G protein hydrolyzes its own bound GTP, converting it back to GDP. But before that occurs, the active protein has an opportunity to diffuse away from the receptor and deliver its message for a prolonged period to its downstream target.
Description
This is a GTPBP4 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
GTPBP4, CRFG, NGB, NOG1
Gene ID
23560
Swiss Prot
Q9BZE4
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human GTPBP4 (NP_036473.2) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:1000-1:2000
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
60 kDa/68 kDa/73 kDa
Observed Molecular Weight
74 kDa
Host or Source
Rabbit
Isotype
IgG

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