Products for Research Use Only

KRR1 Polyclonal Antibody

CAT: 0866-RD83096A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD83096A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The SSU is a large ribonucleoprotein consisting of at least 40 proteins and the U3 small nucleolar RNA. It is involved in pre-rRNA processing and ribosome assembly. The SSU is necessary for the biogenesis of the 18S rRNA. Cells that are depleted of SSU proteins will arrest in the G1 phase of the cell cycle. KRR1, also known as HRB2 (HIV-1 Rev binding protein 2) or RIP-1 (Rev interacting protein 1), is a nonribosomal component of the small subunit processome (SSU) . KRR1 is 381 amino acids in length and is evolutionarily conserved among human, yeast, fly, nematode and rice. KRR1 localizes to the nucleolus and is highly expressed in dividing cells. It contains one conserved KH domain (RNA-binding motif) and is a crucial component of the SSU, required for both rRNA maturation and ribosome biogenesis.
Description
This is a KRR1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
KRR1, HRB2, RIP-1
Gene ID
11103
Swiss Prot
Q13601
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human KRR1 (NP_008974.5) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000 IF 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
36 kDa/43 kDa
Observed Molecular Weight
44 kDa
Host or Source
Rabbit
Isotype
IgG