STAU1 Polyclonal Antibody

CAT: 0866-RD83028A-01Size: 60 μLDry Ice: NoHazardous: No
CAT#:0866-RD83028A-01Size:60 μL
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Background
Staufen is a member of the family of double-stranded RNA (dsRNA) -binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. The human homologue of staufen encoded by STAU, in addition contains a microtubule- binding domain similar to that of microtubule-associated protein 1B, and binds tubulin. The STAU gene product has been shown to be present in the cytoplasm in association with the rough endoplasmic reticulum (RER), implicating this protein in the transport of mRNA via the microtubule network to the RER, the site of translation. Five transcript variants resulting from alternative splicing of STAU gene and encoding three isoforms have been described. Three of these variants encode the same isoform, however, differ in their 5'UTR.
Description
This is a STAU1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
STAU1, PPP1R150, STAU
Gene ID
6780
Swiss Prot
O95793
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human STAU1 (NP_059347.2) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
IHC 1:50-1:100
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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