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EIF4G2 Polyclonal Antibody

CAT: 0866-RD82792A-01Size: 60 μLDry Ice: NoHazardous: No
CAT#:0866-RD82792A-01Size:60 μL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. The protein encoded by this gene shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3; eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexes. In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.
Description
This is a EIF4G2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
EIF4G2, AAG1, DAP5, NAT1, P97
Gene ID
1982
Swiss Prot
P78344
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide of human EIF4G2 (NP_001409.3) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
IHC 1:100-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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