EIF4G1 Polyclonal Antibody

• Background :

  The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly (A) -binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage.

• Description :

  This is a EIF4G1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  DKFZp686A1451, eIF 4 gamma 1, eIF 4G 1, eIF 4G1, eIF-4-gamma 1, eIF-4G 1, eIF-4G1, EIF4 gamma, EIF4F, EIF4G, EIF4G1, EIF4GI, Eukaryotic translation initiation factor 4 gamma 1, IF4G1, p220

• Swiss Prot :

  Q04637

• Accession Number :

  NP_004944

• Reactivity :

  Human

• Immunogen :

  Synthetic peptide of human EIF4G1

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  WB, IHC, ELISA

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Concentration :

  0.5 mg/mL

• Dilution :

  WB 1:500-1:2000, IHC 1:25-1:100

• Buffer :

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Storage Conditions :

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  175 kDa

• Host or Source :

  Rabbit

• Isotype :

  IgG