(KO Validated) APEX1 Polyclonal Antibody
CAT:
866-RD82710A-02
Size:
120 μL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
(KO Validated) APEX1 Polyclonal Antibody
- Background: Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein.
- Synonyms: APEX1,APE,APE1,APEN,APEX,APX,HAP1,REF1
- CAS Number: 9007-83-4
- Gene ID: 328
- Swiss Prot: P27695
- Host: Rabbit
- Reactivity: Human
- Immunogen: Recombinant fusion protein of human APEX1 (NP_542380.1).
- Isotype: IgG
- Conjugation: Unconjugated
- Applications: WB,IF
- Purification: Affinity purification
- Concentration: 1 mg/mL
- Dilution: WB 1:500-1:2000 IF 1:50-1:100
- Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
- Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles.
- Calculated Molecular Weight: 35 kDa
- Observed Molecular Weight: 39 kDa