CDKN1C Polyclonal Antibody

• Background:

  This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.

• Description:

  This is a CDKN1C Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  CDKN1C, BWCR, BWS, KIP2, WBS, p57, p57Kip2

• Gene ID:

  1028

• Swiss Prot:

  P49918

• Reactivity:

  Mouse, Rat

• Immunogen:

  A synthetic peptide of human CDKN1C (NP_000067.1) .

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:2000

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  31 kDa/32 kDa

• Observed Molecular Weight:

  55 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG