CDKN2C Polyclonal Antibody

CAT: 0866-RD82490A-01Size: 60 μLDry Ice: NoHazardous: No
CAT#:0866-RD82490A-01Size:60 μL
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Background
The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. Ectopic expression of this gene was shown to suppress the growth of human cells in a manner that appears to correlate with the presence of a wild-type RB1 function. Studies in the knockout mice suggested the roles of this gene in regulating spermatogenesis, as well as in suppressing tumorigenesis. Two alternatively spliced transcript variants of this gene, which encode an identical protein, have been reported.
Description
This is a CDKN2C Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
CDKN2C, INK4C, p18, p18-INK4C
Gene ID
1031
Swiss Prot
P42773
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human CDKN2C (NP_523240.1) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
IHC 1:50-1:100 IF 1:50-1:100
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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