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PDHA1 Polyclonal Antibody

CAT: 0866-RD82397A-01Size: 60 μLDry Ice: NoHazardous: No
CAT#:0866-RD82397A-01Size:60 μL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO (2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) . The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Description
This is a PDHA1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
PDHA1, PDHA, PDHAD, PDHCE1A, PHE1A
Gene ID
5160
Swiss Prot
P08559
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human PDHA1 (NP_000275.1) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC, IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
40 kDa/43 kDa/44 kDa/47 kDa
Observed Molecular Weight
45 kDa
Host or Source
Rabbit
Isotype
IgG

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