TRIM5 Polyclonal Antibody

• Background :

  The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein forms homo-oligomers via the coilel-coil region and localizes to cytoplasmic bodies. It appears to function as a E3 ubiquitin-ligase and ubiqutinates itself to regulate its subcellular localization. It may play a role in retroviral restriction. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.

• Description :

  This is a TRIM5 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  TRIM5, RNF88, TRIM5alpha

• Gene ID :

  85363

• Swiss Prot :

  Q9C035

• Reactivity :

  Human, Mouse

• Immunogen :

  A synthetic peptide of human TRIM5 (NP_149083.2) .

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  WB

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Concentration :

  1 mg/mL

• Dilution :

  WB 1:500-1:2000

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions :

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  29 kDa/31 kDa/37 kDa/40 kDa/46 kDa/56 kDa

• Observed Molecular Weight :

  50 kDa

• Host or Source :

  Rabbit

• Isotype :

  IgG