TRIM5 Polyclonal Antibody

• Background:

  The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein forms homo-oligomers via the coilel-coil region and localizes to cytoplasmic bodies. It appears to function as a E3 ubiquitin-ligase and ubiqutinates itself to regulate its subcellular localization. It may play a role in retroviral restriction. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.

• Description:

  This is a TRIM5 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  TRIM5, RNF88, TRIM5alpha

• Gene ID:

  85363

• Swiss Prot:

  Q9C035

• Reactivity:

  Human, Mouse

• Immunogen:

  A synthetic peptide of human TRIM5 (NP_149083.2) .

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:2000

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  29 kDa/31 kDa/37 kDa/40 kDa/46 kDa/56 kDa

• Observed Molecular Weight:

  50 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG