TRIM2 Polyclonal Antibody

• Background:

  The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic filaments. It plays a neuroprotective role and functions as an E3-ubiquitin ligase in proteasome-mediated degradation of target proteins. Mutations in this gene can cause early-onset axonal neuropathy. Alternative splicing results in multiple transcript variants.

• Description:

  This is a TRIM2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  TRIM2, CMT2R, RNF86

• Gene ID:

  23321

• Swiss Prot:

  Q9C040

• Reactivity:

  Mouse, Rat

• Immunogen:

  Recombinant fusion protein of human TRIM2 (NP_056086.2) .

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:2000

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  81 kDa/84 kDa

• Observed Molecular Weight:

  81 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG