PSAP Polyclonal Antibody

• Background:

  This gene encodes a highly conserved preproprotein that is proteolytically processed to generate four main cleavage products including saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

• Description:

  This is a PSAP Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  PSAP, GLBA, SAP1

• Gene ID:

  5660

• Swiss Prot:

  P07602

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein of human PSAP (NP_002769.1) .

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB, IHC, IF

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  58 kDa

• Observed Molecular Weight:

  58 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG