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CHRNA4 Polyclonal Antibody

CAT: 0866-RD82259A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD82259A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have been described. Alternative splicing results in multiple transcript variants.
Description
This is a CHRNA4 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
CHRNA4, BFNC, EBN, EBN1, NACHR, NACHRA4, NACRA4
Gene ID
1137
Swiss Prot
P43681
Reactivity
Mouse
Immunogen
Recombinant protein of human CHRNA4
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
60 kDa/69 kDa
Observed Molecular Weight
70 kDa
Host or Source
Rabbit
Isotype
IgG

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