SEMA3C Polyclonal Antibody

• Background :

  This gene encodes a secreted glycoprotein that belongs to the semaphorin class 3 family of neuronal guidance cues. The encoded protein contains an N-terminal sema domain, integrin and immunoglobulin-like domains, and a C-terminal basic domain. Homodimerization and proteolytic cleavage of the C-terminal propeptide are necessary for the function of the encoded protein. It binds a neuropilin co-receptor before forming a heterotrimeric complex with an associated plexin. An increase in the expression of this gene correlates with an increase in cancer cell invasion and adhesion. Naturally occurring mutations in this gene are associated with Hirschsprung disease.

• Description :

  This is a SEMA3C Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  SEMA3C, SEMAE, SemE

• Gene ID :

  10512

• Swiss Prot :

  Q99985

• Reactivity :

  Mouse, Rat

• Immunogen :

  Recombinant fusion protein of human SEMA3C (NP_006370.1) .

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  WB, IF

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Concentration :

  1 mg/mL

• Dilution :

  WB 1:200-1:2000 IF 1:50-1:200

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions :

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  26 kDa/85 kDa

• Observed Molecular Weight :

  85 kDa

• Host or Source :

  Rabbit

• Isotype :

  IgG