Products for Research Use Only

SEMA3C Polyclonal Antibody

CAT: 0866-RD82112A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD82112A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a secreted glycoprotein that belongs to the semaphorin class 3 family of neuronal guidance cues. The encoded protein contains an N-terminal sema domain, integrin and immunoglobulin-like domains, and a C-terminal basic domain. Homodimerization and proteolytic cleavage of the C-terminal propeptide are necessary for the function of the encoded protein. It binds a neuropilin co-receptor before forming a heterotrimeric complex with an associated plexin. An increase in the expression of this gene correlates with an increase in cancer cell invasion and adhesion. Naturally occurring mutations in this gene are associated with Hirschsprung disease.
Description
This is a SEMA3C Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
SEMA3C, SEMAE, SemE
Gene ID
10512
Swiss Prot
Q99985
Reactivity
Mouse, Rat
Immunogen
Recombinant fusion protein of human SEMA3C (NP_006370.1) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:200-1:2000 IF 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
26 kDa/85 kDa
Observed Molecular Weight
85 kDa
Host or Source
Rabbit
Isotype
IgG