Products for Research Use Only

SMG7 Polyclonal Antibody

CAT: 0866-RD82103A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD82103A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a protein that is essential for nonsense-mediated mRNA decay (NMD) ; a process whereby transcripts with premature termination codons are targeted for rapid degradation by a mRNA decay complex. The mRNA decay complex consists, in part, of this protein along with proteins SMG5 and UPF1. The N-terminal domain of this protein is thought to mediate its association with SMG5 or UPF1 while the C-terminal domain interacts with the mRNA decay complex. This protein may therefore couple changes in UPF1 phosphorylation state to the degradation of NMD-candidate transcripts. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Description
This is a SMG7 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
SMG7, C1orf16, EST1C, SGA56M
Gene ID
9887
Swiss Prot
Q92540
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human SMG7 (NP_963863.2) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:200-1:2000
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
122 kDa/127 kDa/131 kDa
Observed Molecular Weight
127 kDa
Host or Source
Rabbit
Isotype
IgG