PTP4A2 Polyclonal Antibody

• Background :

  The protein encoded by this gene belongs to a small class of the protein tyrosine phosphatase (PTP) family. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. PTPs in this class contain a protein tyrosine phosphatase catalytic domain and a characteristic C-terminal prenylation motif. This PTP has been shown to primarily associate with plasmic and endosomal membrane through its C-terminal prenylation. This PTP was found to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), and thus may function as a regulator of GGT II activity. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which suggested its role in tumorigenesis. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 11, 12 and 17.

• Description :

  This is a PTP4A2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  PTP4A2, HH13, HH7-2, HU-PP-1, OV-1, PRL-2, PRL2, PTP4A, PTPCAAX2, ptp-IV1a, ptp-IV1b

• Gene ID :

  8073

• Swiss Prot :

  Q12974

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant fusion protein of human PTP4A2 (NP_536316.1) .

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  IHC, IF

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Concentration :

  1 mg/mL

• Dilution :

  IHC 1:50-1:200 IF 1:50-1:200

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions :

  Store at -20°C. Avoid freeze / thaw cycles.

• Host or Source :

  Rabbit

• Isotype :

  IgG