MDM2 Polyclonal Antibody

CAT: 0866-RD81328A-01Size: 60 μLDry Ice: NoHazardous: No
CAT#:0866-RD81328A-01Size:60 μL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells.
Description
This is a MDM2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
MDM2, ACTFS, HDMX, hdm2
Gene ID
4193
Swiss Prot
Q00987
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human MDM2 (NP_002383.2) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
11-14 kDa/24-55 kDa
Observed Molecular Weight
55 kDa
Host or Source
Rabbit
Isotype
IgG

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