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ACTN1 Polyclonal Antibody

CAT: 0866-RD80645A-01Size: 60 μLDry Ice: NoHazardous: No
CAT#: RD80645A-01Size: 60 μL
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AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene.
Description
This is a ACTN1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
ACTN1, BDPLT15
Gene ID
87
Swiss Prot
P12814
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein of human ACTN1 (NP_001123477.1) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000 IHC 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
102 kDa/103 kDa/105 kDa/107 kDa
Observed Molecular Weight
105 kDa
Host or Source
Rabbit
Isotype
IgG

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