ACTN2 Polyclonal Antibody

• Background :

  Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene.

• Description :

  This is a ACTN2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  ACTN2, CMD1AA, CMH23

• Gene ID :

  88

• Swiss Prot :

  P35609

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant fusion protein of human ACTN2 (NP_001094.1) .

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  WB, IF

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Concentration :

  1 mg/mL

• Dilution :

  WB 1:500-1:2000 IF 1:50-1:200

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions :

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  103 kDa

• Observed Molecular Weight :

  104 kDa

• Host or Source :

  Rabbit

• Isotype :

  IgG