ACTN2 Polyclonal Antibody

CAT: 0866-RD82944A-01Size: 60 μLDry Ice: NoHazardous: No
CAT#:0866-RD82944A-01Size:60 μL
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Background
Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene.
Description
This is a ACTN2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
ACTN2, CMD1AA, CMH23
Gene ID
88
Swiss Prot
P35609
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human ACTN2 (NP_001094.1) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000 IF 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
103 kDa
Observed Molecular Weight
104 kDa
Host or Source
Rabbit
Isotype
IgG

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