AMACR Polyclonal Antibody

• Background:

  This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R) - and (S) -stereoisomers. The conversion to the (S) -stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene.

• Description:

  This is a AMACR Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  AMACR, AMACRD, CBAS4, P504S, RACE, RM

• Gene ID:

  23600

• Swiss Prot:

  Q9UHK6

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein of human AMACR (NP_976316.1) .

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:2000

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  22 kDa/25 kDa/42 kDa/43 kDa

• Observed Molecular Weight:

  43 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG