PCBP1 Polyclonal Antibody

CAT: 0866-RD80389A-01Size: 60 μLDry Ice: NoHazardous: No
CAT#:0866-RD80389A-01Size:60 μL
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This intronless gene is thought to have been generated by retrotransposition of a fully processed PCBP-2 mRNA. This gene and PCBP-2 have paralogues (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. The protein encoded by this gene appears to be multifunctional. It along with PCBP-2 and hnRNPK corresponds to the major cellular poly (rC) -binding protein. It contains three K-homologous (KH) domains which may be involved in RNA binding. This encoded protein together with PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability.
Description
This is a PCBP1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
PCBP1, HEL-S-85, HNRPE1, HNRPX, hnRNP-E1, hnRNP-X
Gene ID
5093
Swiss Prot
Q15365
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide of human PCBP1 (NP_006187.2) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC, IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000 IHC 1:50-1:100 IF 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
37 kDa
Observed Molecular Weight
37 kDa
Host or Source
Rabbit
Isotype
IgG

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