CD53 Polyclonal Antibody

• Background:

  The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. It contributes to the transduction of CD2-generated signals in T cells and natural killer cells and has been suggested to play a role in growth regulation. Familial deficiency of this gene has been linked to an immunodeficiency associated with recurrent infectious diseases caused by bacteria, fungi and viruses. Alternative splicing results in multiple transcript variants.

• Description:

  This is a CD53 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  CD53, MOX44, TSPAN25

• Gene ID:

  963

• Swiss Prot:

  P19397

• Reactivity:

  Human, Mouse

• Immunogen:

  Recombinant fusion protein of human CD53 (NP_000551.1) .

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:1000-1:4000

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  24 kDa

• Observed Molecular Weight:

  35 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG