CD59 Polyclonal Antibody

CAT: 0866-RD90706A-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0866-RD90706A-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction.
Description
This is a CD59 Polyclonal antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
16.3A5,1F5,1F5 antigen,20 kDa homologous restriction factor, CD 59, CD_antigen=CD59, CD59, CD59 antigen, CD59 antigen complement regulatory protein , CD59 antigen p18 20, CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5, EJ16, EJ30, EL32 and
Swiss Prot
P13987
Reactivity
Human
Immunogen
Recombinant Human CD59 protein expressed by E.coli
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal antibody
Applications
WB, IHC
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:1000, IHC 1:250-1:500
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH 7.4
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
124kDa
Observed Molecular Weight
110kDa
Host or Source
Rabbit
Isotype
IgG

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