CD59 Polyclonal Antibody

• Background :

  This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction.

• Description :

  This is a CD59 Polyclonal antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  16.3A5,1F5,1F5 antigen,20 kDa homologous restriction factor, CD 59, CD_antigen=CD59, CD59, CD59 antigen, CD59 antigen complement regulatory protein , CD59 antigen p18 20, CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5, EJ16, EJ30, EL32 and

• Swiss Prot :

  P13987

• Reactivity :

  Human

• Immunogen :

  Recombinant Human CD59 protein expressed by E.coli

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Polyclonal antibody

• Applications :

  WB, IHC

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Concentration :

  1 mg/mL

• Dilution :

  WB 1:500-1:1000, IHC 1:250-1:500

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH 7.4

• Storage Conditions :

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  124kDa

• Observed Molecular Weight :

  110kDa

• Host or Source :

  Rabbit

• Isotype :

  IgG