CCNH Polyclonal Antibody

CAT: 0866-RD80192A-01Size: 60 μLDry Ice: NoHazardous: No
CAT#:0866-RD80192A-01Size:60 μL
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Background
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, thus functions as a CDK-activating kinase (CAK) . This cyclin and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes. They participate in two different transcriptional regulation processes, suggesting an important link between basal transcription control and the cell cycle machinery. A pseudogene of this gene is found on chromosome 4. Alternate splicing results in multiple transcript variants.
Description
This is a CCNH Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
CCNH, CAK, CycH, p34, p37, cyclin-H
Gene ID
902
Swiss Prot
P51946
Reactivity
Human
Immunogen
Recombinant fusion protein of human CCNH (NP_001230.1) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
37 kDa
Observed Molecular Weight
36 kDa
Host or Source
Rabbit
Isotype
IgG

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