UACA Polyclonal Antibody

• Background :

  Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. Promotes apoptosis by regulating three pathways, apoptosome up-regulation, LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation. Regulates the redistribution of APAF1 into the nucleus after proapoptotic stress. Down-regulates the expression of LGALS3 by inhibiting NFKB1 (By similarity) .

• Description :

  This is a UACA Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  FLJ10128, KIAA1561, MGC141967, MGC141969, Nuclear membrane binding protein, NUCLING, UACA, UACA, Uveal autoantigen with coiled coil domains and ankyrin repeats, Uveal autoantigen with coiled-coil domains and ankyrin repeats

• Swiss Prot :

  Q9BZF9

• Accession Number :

  BC113407

• Reactivity :

  Human, Mouse

• Immunogen :

  Fusion protein of human UACA

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  IHC, ELISA

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Concentration :

  0.8 mg/mL

• Dilution :

  IHC 1:30-150, ELISA 1:2000-10000

• Buffer :

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Storage Conditions :

  Store at -20°C. Avoid freeze / thaw cycles.

• Host or Source :

  Rabbit

• Isotype :

  IgG