TRPC4AP Polyclonal Antibody

• Background:

  TRPC4AP (transient receptor potential cation channel, subfamily C, member 4 associated protein), also known as TRUSS or TRRP4AP, is a 797 amino acid protein that is expressed in a variety of tissues, with highest expression in liver, heart, testis and brain. Thought to function as a scaffolding protein, TRPC4AP interacts with TNF-R1 and may both link TNF-R1 to the IKK signalsome complex, and participate in the activation of NFκB p50, an event that occurs in response to TNF-R1 ligation. TRPC4AP exists as multiple alternatively spliced isoforms that are encoded by a gene whicHuman, Mouseaps to human chromosome 20. Comprising approximately 2% of the human genome, chromosome 20 contains nearly 63 million bases that encode over 600 genes, some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome.

• Synonyms:

  C20orf188, TRPC4AP,Chromosome 20 open reading frame 188,Protein TAP1,Protein TRUSS,Short transient receptor potential channel 4 associated protein,Short transient receptor potential channel 4-associated protein,TAP1 protein,TNF receptor ubiquitous scaffolding/signaling protein,TNF-receptor ubiquitous scaffolding/signaling protein,TP4AP,Transient receptor potential cation channel,subfamily C,member 4 associated protein,Trp4 associated protein,Trp4-associated protein,Trpc4 associated protein,Trpc4-associated protein,TRPC4AP,TRRP4AP,TRUSS,Tumor necrosis factor receptor-associated ubiquitous scaffolding and signaling protein

• Swiss Prot:

  Q8TEL6

• Accession Number:

  BC013144

• Host:

  Rabbit

• Reactivity:

  Human,Mouse

• Immunogen:

  Fusion protein of human TRPC4AP

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Conjugation:

  Unconjugated

• Applications:

  IHC,ELISA

• Purification:

  Affinity purification

• Concentration:

  0.9 mg/mL

• Dilution:

  IHC 1:30-150, ELISA 1:2000-10000

• Buffer:

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• CAS Number:

  9007-83-4