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PTAFR Polyclonal Antibody

CAT: 0866-RD78729A-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0866-RD78729A-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a seven-transmembrane G-protein-coupled receptor for platelet-activating factor (PAF) that localizes to lipid rafts and/or caveolae in the cell membrane. PAF (1-0-alkyl-2-acetyl-sn-glycero-3-phosphorylcholine) is a phospholipid that plays a significant role in oncogenic transformation, tumor growth, angiogenesis, metastasis, and pro-inflammatory processes. Binding of PAF to the PAF-receptor (PAFR) stimulates numerous signal transduction pathways including phospholipase C, D, A2, mitogen-activated protein kinases (MAPKs), and the phosphatidylinositol-calcium second messenger system. Following PAFR activation, cells become rapidly desensitized and this refractory state is dependent on PAFR phosphorylation, internalization, and down-regulation. Alternative splicing results in multiple transcript variants.
Description
This is a PTAFR Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
OTTHUMP00000004041, OTTMUSP00000010350, PAF R, PAF receptor, PAF-R, PAFr, Platelet activating factor receptor, Platelet-activating factor receptor, PTAFR, PTAFR, RP23-470B20.1
Swiss Prot
P25105
Accession Number
NP_000943
Reactivity
Human
Immunogen
Synthetic peptide of human PTAFR
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
0.5 mg/mL
Dilution
IHC 1:25-1:100
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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