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MCM4 Polyclonal Antibody

CAT: 0866-RD78574A-01Size: 20 µLDry Ice: NoHazardous: No
CAT#:0866-RD78574A-01Size:20 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 6 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of this protein by CDC2 kinase reduces the DNA helicase activity and chromatin binding of the MCM complex. This gene is mapped to a region on the chromosome 8 head-to-head next to the PRKDC/DNA-PK, a DNA-activated protein kinase involved in the repair of DNA double-strand breaks. Alternatively spliced transcript variants encoding the same protein have been reported.
Description
This is a MCM4 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
19G, AI325074, AU045576, CDC 21, CDC 54, CDC21, CDC21 homolog, CDC21, S. pombe, homolog of, CDC54, Cell division cycle 21, S. pombe, homolog of, DNA replication licensing factor MCM 4, DNA replication licensing factor MCM4, hCdc 21, hCdc21, Homolog of S. pombe cell devisio
Swiss Prot
P33991
Accession Number
NP_877423
Reactivity
Human, Mouse
Immunogen
Synthetic peptide of human MCM4
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
0.3 mg/mL
Dilution
WB 1:500-1:2000, IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
97 kDa
Host or Source
Rabbit
Isotype
IgG

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