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MCM3 Polyclonal Antibody

CAT: 0866-RD70114A-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0866-RD70114A-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with mCM5/CDC46. This protein also interacts with and is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. Two transcript variants encoding different isoforms have been found for this gene.
Description
This is a MCM3 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
Cervical cancer proto oncogene 5, DNA polymerase alpha holoenzyme associated P1, HCC 5, HCC5, hRlf beta subunit, Human cervical cancer proto oncogene 5, MCM 3, MGC1157, Minichromosome maintenance complex component 3, P1 h, P1 MCM3, P1.h, p102, Replication licensing fa
Swiss Prot
P25205
Reactivity
Human
Immunogen
Recombinant Human DNA replication licensing factor MCM3 protien
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
2 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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