Products for Research Use Only

Claudin 8 Polyclonal Antibody

CAT: 0866-RD78517A-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0866-RD78517A-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This protein plays important roles in the paracellular cation barrier of the distal renal tubule, and in the paracellular barrier to prevent sodium back-leakage in distal colon. Differential expression of this gene has been observed in colorectal carcinoma and renal cell tumors, and along with claudin-7, is an immunohistochemical marker for the differential diagnosis of chromophobe renal cell carcinoma and renal oncocytoma.
Description
This is a Claudin 8 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
Claudin 8, Claudin-8, CLD8, Cldn8, Epididymis secretory protein Li 79, HEL S 79, OTTHUMP00000101915
Swiss Prot
P56748
Accession Number
NP_955360
Reactivity
Human
Immunogen
Synthetic peptide of human CLDN8
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
0.5 mg/mL
Dilution
IHC 1:100-1:300
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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