Claudin 1 Polyclonal Antibody

• Background:

  Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome.

• Description:

  This is a Claudin 1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  Claudin-1, Claudin1, CLD 1, CLD1, CLD1, CLDN 1, Cldn1, ILVASC, SEMP 1, SEMP1, Senescence associated epithelial membrane protein 1, Senescence associated epithelial membrane protein, Senescence-associated epithelial membrane protein

• Swiss Prot:

  O95832

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Synthesized peptide derived from the C-terminal region of human Claudin-1

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB, IHC-p, IF, ELISA

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:40000

• Buffer:

  PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  23 kDa

• Observed Molecular Weight:

  22 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG