EPOR Polyclonal Antibody

• Background :

  This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.

• Description :

  This is a EPOR Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  EPO R, EPO-R, epor, EPOR, Erythropoietin receptor, Erythropoietin receptor precursor, MGC138358

• Swiss Prot :

  P19235

• Accession Number :

  NP_000112

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Synthetic peptide of human EPOR

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  IHC, ELISA

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Concentration :

  0.7 mg/mL

• Dilution :

  IHC 1:50-1:200

• Buffer :

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Storage Conditions :

  Store at -20°C. Avoid freeze / thaw cycles.

• Host or Source :

  Rabbit

• Isotype :

  IgG