ACVR2A Polyclonal Antibody

• Background:

  This gene encodes activin A type II receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling, and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases.

• Description:

  This is a ACVR2A Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  Activin A receptor type IIA, Activin receptor type 2A, Activin receptor type IIA, Activin receptor type-2A, ACTR 2, ACTR IIA, ACTR-IIA, ACTR2, ACTRII, ACTRIIA, Acvr 2, Acvr 2A, Acvr2, ACVR2A, AVR2A, OTTHUMP00000197918

• Swiss Prot:

  P27037

• Accession Number:

  NP_001607

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Synthetic peptide of human ACVR2A

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB, ELISA

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1.2 mg/mL

• Dilution:

  WB 1:500-1:2000

• Buffer:

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  58 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG